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Vanda Licenses Lilly CNS Compound

NK-1R antagonist license includes $99 million in milestones

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Vanda Pharmaceuticals has acquired an exclusive world-wide license from Lilly to develop and commercialize LY686017, a small molecule neurokinin 1 receptor (NK-1R) antagonist for all human indications. The compound will be known as VLY-686.   NK-1R antagonists have been evaluated in a number of indications including chemotherapy-induced nausea and vomiting, post-operative nausea and vomiting, alcohol dependence, anxiety, depression, and pruritus. VLY-686 has demonstrated proof-of-concept in ...

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